Alec Pierce injury update as Colts WR exits against Chiefs

Indianapolis Colts wide receiver Alec Pierce left Sunday night’s game against the Kansas City Chiefs with an apparent heel injury.

Pierce appeared to suffer the injury while running an out route in the second quarter against Chiefs cornerback Nohl Williams.

He hobbled at the end of the play before leaving the field. Here are the latest updates on Pierce:

De’Zhaun Stribling, SF (ankle)

De’Zhaun Stribling of the San Francisco 49ers is attended to by trainers after an injury in the second quarter of the NFL football game against Los Angeles Rams at the Melbourne Cricket Ground on September 11, 2026, in Melbourne, Australia.

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De’Zhaun Stribling, SF (ankle)

De’Zhaun Stribling of the San Francisco 49ers is attended to by trainers after an injury in the second quarter of the NFL football game against Los Angeles Rams at the Melbourne Cricket Ground on September 11, 2026, in Melbourne, Australia.

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Tua Tagovailoa, ATL (oblique)

Tua Tagovailoa of the Atlanta Falcons runs through drills during OTA’s at IBM Performance Field on May 27, 2026, in Flowery Branch, Georgia.

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A.J. Brown, NE (ankle) – injured reserve

A.J. Brown of the New England Patriots reacts after being injured in a play against the Seattle Seahawks during the third quarter in the game at Lumen Field on September 09, 2026 in Seattle, Washington.

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Sam Darnold, SEA (hip)

New England Patriots defensive end Dre’Mont Jones sacks Seattle Seahawks quarterback Sam Darnold during the first quarter at Lumen Field.

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Brock Bowers, LV (knee)

Brock Bowers of the Las Vegas Raiders waves to fans after warming up before a preseason game against the Arizona Cardinals at Allegiant Stadium on August 13, 2026, in Las Vegas, Nevada.

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Treveyon Henderson, NE (ankle)

Treveyon Henderson of the New England Patriots looks on prior to Super Bowl LX between the Seattle Seahawks and the New England Patriots at Levi’s Stadium on February 08, 2026, in Santa Clara, California.

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Rome Odunze, CHI (calf)

Rome Odunze of the Chicago Bears catches a pass during Chicago Bears Training Camp at Halas Hall on July 29, 2026, in Lake Forest, Illinois.

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Alvin Kamara, NO (knee)

Alvin Kamara of the New Orleans Saints on the sidelines before a preseason game between the New Orleans Saints and the Los Angeles Rams at SoFi Stadium on August 22, 2026, in Inglewood, California.

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Zach Charbonnet, SEA (knee) – PUP list

Zach Charbonnet of the Seattle Seahawks runs with the ball against by Deommodore Lenoir of the San Francisco 49ers during the third quarter of a game at Levi’s Stadium on January 03, 2026, in Santa Clara, California.

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Isiah Pacheco, DET (back) – Injured reserve

Isiah Pacheco of the Detroit Lions during Detroit Lions Training Camp at Detroit Lions Meijer Performance Center on July 29, 2026, in Allen Park, Michigan.

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Jordyn Tyson, NO (hamstring) – Injured reserve

Jordyn Tyson of the New Orleans Saints participates in drills during training camp at Ochsner Sports Performance Center on July 30, 2026, in Metairie, Louisiana.

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Tank Dell, HOU (knee) – Injured reserve

Tank Dell of the Houston Texans runs to the practice facility during Houston Texans training camp at Houston Methodist Training Center on August 01, 2026, in Houston, Texas.

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Christian Kirk, SF (calf) – Injured reserve

Christian Kirk of the Jacksonville Jaguars is introduced against the San Francisco 49ers during the game at EverBank Field on November 12, 2023, in Jacksonville, Florida.

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Ricky Pearsall, SF (knee) – Out for season

Ricky Pearsall of the San Francisco 49ers works out during training camp practice at SAP Performance Facility on July 27, 2026, in Santa Clara, California.

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Chris Brazzell, CAR (knee) – Out for season

Chris Brazzell II of the Carolina Panthers warms up during the Carolina Panthers Training Camp at Carolina Panthers Practice Fields on July 23, 2026, in Charlotte, North Carolina.

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Jayden Higgins, HOU (knee) – Out for season

Jayden Higgins of the Houston Texans catches a pass for a touchdown during the second quarter of the game against the Indianapolis Colts at NRG Stadium on January 04, 2026, in Houston, Texas.

Pierce, who re-signed with the team on a four-year, $114 million contract this offseason, was listed as questionable to return. Shortly after, the Colts ruled out Pierce for the remainder of the game.

Pierce missed extended time during the summer after undergoing a clean-up procedure on his left ankle in March.