UFC Oklahoma City: Dricus Du Plessis vs. Kamaru Usman odds, what to know

Dricus Du Plessis returns for his first fight since losing the middleweight title to take on former welterweight champion Kamaru Usman.

Du Plessis (23-3 MMA, 9-1 UFC) was last in action at UFC 319 in August 2025, where he dropped the title to Khamzat Chimaev. It was his first loss under the UFC banner, snapping an 11-fight winning streak. Du Plessis won the title by defeating Sean Strickland at UFC 297 and notched two title defenses.

Usman (21-4 MMA, 16-3 UFC) returns to the middleweight division to take on the former champ. His last appearance was a main event win against Joaquin Buckley last June in a welterweight bout. In the fight prior, he dropped a short-notice majority decision to Chimaev at 185 pounds.

According to DraftKings, Du Plessis is a comfortable -340 favorite to bounce back against Usman, who opens as a +270 underdog.

Where: Paycom Center, Oklahoma City, Okla.